Tulane University Translational Science Institute (TUTSI)


Low-Carbohydrate Dietary Pattern on Glycemic Outcomes Trial

About the Study

  • ADEPT (Low-Carbohydrate Dietary Pattern on Glycemic Outcomes Trial)
  • A current JFI Project

Project Summary

The objective of this randomized clinical trial is to examine the effects of a behavioral dietary intervention that promotes a low-carbohydrate diet compared with usual diet in individuals with or at high risk of type 2 diabetes. The primary outcome will be difference in change in a marker of blood sugar in the intervention group compared with the usual diet group over a 6-month period. Secondary outcomes will include other measures of glycemic control and other cardiometabolic risk factors.

Project Lead

Kirsten Dorans, ScD (Assistant Professor, Department of Epidemiology)

What is the ADEPT Trial?

  • The ADEPT trial is being done to learn if a low-carbohydrate diet reduces blood sugar and other markers of health, including blood pressure.
  • In this voluntary study, we will randomly put people into two groups. You have an equal chance of being in either group. 
  • One group will help participants modify their diet and eat a low-carbohydrate diet and the other group will continue with their usual diet. 
  • The goal is to see if people who participate in the low-carbohydrate group will have lower blood sugar than those eating their usual diet.
  • Visits will take place at 1440 Canal Street, New Orleans, LA 70112

    What are the benefits of participating in the study?

    • You will receive multiple blood pressure and weight measurements during the trial. At the end of the study, we will provide you and your physician with blood pressure, weight, and laboratory results.
    • You will receive one or more free counseling sessions to learn how to make personalized dietary changes.
    • Knowledge gained from this study may help patients with or at high risk of diabetes in the future.
    • Once in the study, you will receive gift cards for participating.